Ephrin-A3/EFNA3, His, Human/Cynomolgus/Rhesus macaque
Ephrin-A3/EFNA3, His, Human/Cynomolgus/Rhesus Macaque

The purity of Ephrin-A3/EFNA3, His, Human/Cynomolgus/Rhesus macaque is greater than 95% as determined by SEC-HPLC.

Ephrin-A3/EFNA3, His, Human/Cynomolgus/Rhesus Macaque

Ephrin-A3/EFNA3, His, Human/Cynomolgus/Rhesus macaque on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

Ephrin-A3/EFNA3, His, Human/Cynomolgus/Rhesus macaque

Interaction of Eph receptor tyrosine kinases with their membrane bound ephrin ligands initiates bidirectional signaling events that regulate cell migratory and adhesive behavior. Whole-mount in situ hybridization revealed overlapping expression of the Epha1 receptor and its high-affinity ligands ephrin A1 (Efna1) and ephrin A3 (Efna3) in the primitive streak and the posterior paraxial mesoderm during early mouse development.
Z05967
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Product Introduction
Species Human/Cynomolgus/Rhesus macaque
Protein Construction
Ephrin-A3/EFNA3 (Gln23-Ser213)_x000D_
Accession # P52797-1(Human) / A0A2K5VZR7(Cynomolgus) / NP_001252612.1(Rhesus macaque)		 His
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
> 95% as determined by HPLC
Endotoxin Level Less than 1EU per μg by the LAL method.
Expression System HEK293
Theoretical Molecular Weight 22.51 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 40-50 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

Examples
  • Ephrin-A3/EFNA3, His, Human/Cynomolgus/Rhesus Macaque
    • Ephrin-A3/EFNA3, His, Human/Cynomolgus/Rhesus Macaque

    The purity of Ephrin-A3/EFNA3, His, Human/Cynomolgus/Rhesus macaque is greater than 95% as determined by SEC-HPLC.

  • Ephrin-A3/EFNA3, His, Human/Cynomolgus/Rhesus Macaque
    • Ephrin-A3/EFNA3, His, Human/Cynomolgus/Rhesus Macaque

    Ephrin-A3/EFNA3, His, Human/Cynomolgus/Rhesus macaque on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.


Background
Target Background Interaction of Eph receptor tyrosine kinases with their membrane bound ephrin ligands initiates bidirectional signaling events that regulate cell migratory and adhesive behavior. Whole-mount in situ hybridization revealed overlapping expression of the Epha1 receptor and its high-affinity ligands ephrin A1 (Efna1) and ephrin A3 (Efna3) in the primitive streak and the posterior paraxial mesoderm during early mouse development.
Synonyms Ephrin-A3; Ephrin A3; EFL-2; EHK1 ligand; EHK1-L; EFNA3; EPLG3; LERK3

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.