VSIG3/IGSF11, His, Human
VSIG3/IGSF11, His, Human

The purity of VSIG3/IGSF11, His, Human is greater than 95% as determined by SEC-HPLC.

VSIG3/IGSF11, His, Human

VSIG3/IGSF11, His, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

VSIG3/IGSF11, His, Human

VSIG3/IGSF11, His, Human on CM5 Chip via Protein A can bind Human VSIG3, His Tag with an affinity constant of 14.44 μM as determined in SPR assay (Biacore T200).

VSIG3/IGSF11, His, Human

Immunoglobulin superfamily member 11 (IgSF11), a homophilic adhesion molecule that preferentially expressed in the brain, is a dual-binding partner of the postsynaptic scaffolding protein PSD-95 and AMPA glutamate receptors (AMPARs).
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Product Introduction
Species Human
Protein Construction
VSIG3/IGSF11 (Leu23-Gly241)_x000D_
Accession # Q5DX21-1		 His
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
> 95% as determined by HPLC
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Human B7­H5, hFc Tag captured on CM5 Chip via Protein A can bind VSIG3/IGSF11, His, Human in SPR assay (Biacore T200). Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 24.31 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 35-40 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

Examples
  • VSIG3/IGSF11, His, Human
    • VSIG3/IGSF11, His, Human

    The purity of VSIG3/IGSF11, His, Human is greater than 95% as determined by SEC-HPLC.

  • VSIG3/IGSF11, His, Human
    • VSIG3/IGSF11, His, Human

    VSIG3/IGSF11, His, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

  • VSIG3/IGSF11, His, Human
    • VSIG3/IGSF11, His, Human

    VSIG3/IGSF11, His, Human on CM5 Chip via Protein A can bind Human VSIG3, His Tag with an affinity constant of 14.44 μM as determined in SPR assay (Biacore T200).


Background
Target Background Immunoglobulin superfamily member 11 (IgSF11), a homophilic adhesion molecule that preferentially expressed in the brain, is a dual-binding partner of the postsynaptic scaffolding protein PSD-95 and AMPA glutamate receptors (AMPARs).
Synonyms IgSF11; Bt-IGSF; Bt IGSF; BtIGSF; VSIG3; CXADRL1; CT119

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.