TSLP hFc Chimera, Human
TSLP HFc Chimera, Human

Loaded TSLP hFc Chimera, Human, hFc Tag on ProA-Biosensor can bind Human TSLPR, His Tag with an affinity constant of 82.50 nM as determined in BLI assay (Gator® Prime).

TSLP HFc Chimera, Human

Immobilized TSLP hFc Chimera, Human, hFc Tag at 5 μg/ml (100 μI/well) on the plate. Dose response curve for Human TSLPR, His Tag with the EC50 of 0.50 μg/ml determined by ELISA.

TSLP HFc Chimera, Human

Immobilized TSLP hFc Chimera, Human, hFc Tag at 2 μg/ml (100 μI/well) on the plate. Dose response curve for Biotinylated Anti-TSLP Antibody, hFc Tag with the EC50 of 87.0ng/ml determined by ELISA.

TSLP HFc Chimera, Human

The purity of TSLP hFc Chimera, Human is greater than 95% as determined by SEC-HPLC.

TSLP HFc Chimera, Human

TSLP hFc Chimera, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

TSLP hFc Chimera, Human

Thymic Stromal Lymphopoietin (TSLP) was originally identified as an activity from the conditioned medium of a mouse thymic stromal cell line that promoted the development of B cells. Cytokine that induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c dendritic cells. Can induce allergic inflammation by directly activating mast cells.
Z05929
¥72,752.00

Ask us a question
Product Introduction
Species Human
Protein Construction
TSLP (Tyr29-Gln159)_x000D_
Accession # Q969D9-1		 hFc
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
Endotoxin Level Less than 1 EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA. Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 41.69 kDa
Apparent Molecular Weight Due to furin cleavage site, the protein migrates to 38-42 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.

Examples
  • TSLP HFc Chimera, Human
    • TSLP HFc Chimera, Human

    Loaded TSLP hFc Chimera, Human, hFc Tag on ProA-Biosensor can bind Human TSLPR, His Tag with an affinity constant of 82.50 nM as determined in BLI assay (Gator® Prime).

  • TSLP HFc Chimera, Human
    • TSLP HFc Chimera, Human

    Immobilized TSLP hFc Chimera, Human, hFc Tag at 5 μg/ml (100 μI/well) on the plate. Dose response curve for Human TSLPR, His Tag with the EC50 of 0.50 μg/ml determined by ELISA.

  • TSLP HFc Chimera, Human
    • TSLP HFc Chimera, Human

    Immobilized TSLP hFc Chimera, Human, hFc Tag at 2 μg/ml (100 μI/well) on the plate. Dose response curve for Biotinylated Anti-TSLP Antibody, hFc Tag with the EC50 of 87.0ng/ml determined by ELISA.

  • TSLP HFc Chimera, Human
    • TSLP HFc Chimera, Human

    The purity of TSLP hFc Chimera, Human is greater than 95% as determined by SEC-HPLC.

  • TSLP HFc Chimera, Human
    • TSLP HFc Chimera, Human

    TSLP hFc Chimera, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.


Background
Target Background Thymic Stromal Lymphopoietin (TSLP) was originally identified as an activity from the conditioned medium of a mouse thymic stromal cell line that promoted the development of B cells. Cytokine that induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c dendritic cells. Can induce allergic inflammation by directly activating mast cells.
Synonyms thymic stromal lymphopoietin; TSLP

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.