TREML2/TLT-2, His, Human

TREML2/TLT-2, His, Human

As an important family member of triggering receptor expressed on myeloid cells (TREM), TREM-like transcript 2 gene (TREML2) locates on human chromosome 6p21.1, a newly-identified hot zone for AD susceptibility, and encodes atransmembrane immune receptor. Emerging evidence implied a potential role of TREML2 in the susceptibility and pathogenesis of AD.
Z05924
¥76,483.00

Ask us a question
Product Introduction
Species Human
Protein Construction
REML2/TLT-2 (Gly19-Ser268)_x000D_
Accession # Q5T2D2		 His
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
> 95% as determined by HPLC
Endotoxin Level Less than 1EU per μg by the LAL method.
Expression System HEK293
Theoretical Molecular Weight 28.2 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 73-80 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

Background
Target Background As an important family member of triggering receptor expressed on myeloid cells (TREM), TREM-like transcript 2 gene (TREML2) locates on human chromosome 6p21.1, a newly-identified hot zone for AD susceptibility, and encodes atransmembrane immune receptor. Emerging evidence implied a potential role of TREML2 in the susceptibility and pathogenesis of AD.
Synonyms TLT-2; C6orf76; dJ238O23.1; FLJ13693; MGC149715; MGC149716; TREML2; UNQ6268/PRO20473

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.