TGF-beta RII/TGFBR2, mFc Chimera, Avi, Human

TGF-beta RII/TGFBR2, mFc Chimera, Avi, Human

The TGFBR2 gene provides instructions for making a protein called transforming growth factor-beta (TGF-β) receptor type 2. This receptor transmits signals from the cell surface into the cell through a process called signal transduction. Through this type of signaling, the environment outside the cell affects activities inside the cell such as stimulation of cell growth and division.
Z05872
¥63,425.00

Ask us a question
Product Introduction
Species Human
Protein Construction
TGF-beta RII/TGFBR2 (Ile24-Asp159)_x000D_
Accession # P37173-1		 mFc (IgG1) Avi
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE
> 95% as determined by HPLC
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA. Immobilized TGF-beta RII/TGFBR2, mFc Chimera, Avi, Human at 1μg/ml (100μl/well) on the plate can bind Biotinylated Human Mature TGF beta 3, Avi Tag. Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 44 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 55-70 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

Background
Target Background The TGFBR2 gene provides instructions for making a protein called transforming growth factor-beta (TGF-β) receptor type 2. This receptor transmits signals from the cell surface into the cell through a process called signal transduction. Through this type of signaling, the environment outside the cell affects activities inside the cell such as stimulation of cell growth and division.
Synonyms TGFR2; TGFBR2; TbetaR-II; TGFβR2; TbetaR-II; TGFβR2; AAT3; FAA3; LDS1B; LDS2; LDS2B; MFS2; RIIC; TAAD2; TβR-II; TβR-II

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.