TENM2, His, Human
TENM2, His, Human

TENM2, His, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 90%.

TENM2, His, Human

Teneurin-2 is a member of a novel family of transmembrane proteins characterized to date in fish, birds, mammals, and Drosophila (e.g., the pair-rule gene product Ten-m). Teneurin-2, a vertebrate homologue of the Drosophila pair-rule gene ten-m/odz, is revealed to be a membrane-bound transcription regulator. In the nucleus, the intracellular domain of teneurin-2 colocalizes with promyelocytic leukemia (PML) protein in nuclear bodies implicated in transcription control.
Z05867
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Product Introduction
Species Human
Protein Construction
His TENM2 (Gly401-Asn841)_x000D_
Accession # Q9NT68-1
N-term C-term
Purity > 90% as determined by Bis-Tris PAGE
Endotoxin Level Less than 1 EU per μg by the LAL method.
Expression System HEK293
Theoretical Molecular Weight 48.48 kDa
Apparent Molecular Weight The protein cleaved to 55-65 kDa, 38-43 kDa and 25-30 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22 μm filtered solution in PBS, 2 mM DTT (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

Examples
  • TENM2, His, Human
    • TENM2, His, Human

    TENM2, His, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 90%.


Background
Target Background Teneurin-2 is a member of a novel family of transmembrane proteins characterized to date in fish, birds, mammals, and Drosophila (e.g., the pair-rule gene product Ten-m). Teneurin-2, a vertebrate homologue of the Drosophila pair-rule gene ten-m/odz, is revealed to be a membrane-bound transcription regulator. In the nucleus, the intracellular domain of teneurin-2 colocalizes with promyelocytic leukemia (PML) protein in nuclear bodies implicated in transcription control.
Synonyms Teneurin-2; Ten-2; Tenascin-M2; Ten-m2; KIAA1127; ODZ2; TNM2

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.