STAT4, His, Human

STAT4, His, Human

Signal transducer and activator of transcription 4 (STAT4) is a member of the STAT family and localizes to the cytoplasm. STAT4 is phosphorylated after a variety of cytokines bind to the membrane, and then dimerized STAT4 translocates to the nucleus to regulate gene expression.
Z05858
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Product Introduction
Species Human
Protein Construction
His STAT4 (Met1-Glu748)
Accession # Q14765
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
Endotoxin Level Less than 1EU per μg by the LAL method.
Expression System Baculovirus-Insect Cells
Theoretical Molecular Weight 87.75 kDa
Apparent Molecular Weight The protein has a predicted MW of 87.75 kDa same as Bis-Tris PAGE result.
Formulation Supplied as 0.22 μm filtered solution in 20mM Tris, 500mM NaCl, 20% glycerol, 0.5mM DTT (pH 7.5).
Concentration Verified by one or more methods from A280/Bioactivity/BCA/Bradford.
Storage & Stability This product remains stable for 6 months at -80°C or below. Avoid repeated freeze-thaw cycles.

Background
Target Background Signal transducer and activator of transcription 4 (STAT4) is a member of the STAT family and localizes to the cytoplasm. STAT4 is phosphorylated after a variety of cytokines bind to the membrane, and then dimerized STAT4 translocates to the nucleus to regulate gene expression.
Synonyms STAT4; SLEB11

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.