SCF, Human

SCF, Human

Kit-ligand (Kitl) also known as steel factor, stem cell factor and mast cell growth factor plays a crucial role in the development and maintenance of the melanocyte lineage in adult skin. Kitl exerts permanent survival, proliferation and migration functions in Kit receptor-expressing melanocytes.
Z05798
¥46,636.00

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Product Introduction
Species Human
Protein Construction
SCF (Glu26-Ala189)_x000D_
Accession # P21583-1
Purity > 95% as determined by Bis-Tris PAGE
Endotoxin Level Less than 0.02EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA. Immobilized SCF, Human at 2μg/ml (100μl/well) on the plate can bind Human CD117, hFc Tag. Test result was comparable to standard batch. Measured in a cell proliferation assay using Mo7e cells. The ED50 for this effect is 1­8 ng/mL. Test result was comparable to standard batch.
Expression System E.coli
Theoretical Molecular Weight 18.45 kDa
Apparent Molecular Weight The protein has a predicted MW of 18.45 kDa same as Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

Background
Target Background Kit-ligand (Kitl) also known as steel factor, stem cell factor and mast cell growth factor plays a crucial role in the development and maintenance of the melanocyte lineage in adult skin. Kitl exerts permanent survival, proliferation and migration functions in Kit receptor-expressing melanocytes.
Synonyms MGF; c-Kit ligand; sKITLG; KITLG; FPH2; KL-1; Kitl; SF; SHEP7; KL

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.