S100A8, His, Human
S100A8, His, Human

The purity of S100A8, His, Human is greater than 95% as determined by SEC-HPLC.

S100A8, His, Human

S100A8, His, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

S100A8, His, Human

S100A8 and S100A9 (also known as MRP8 and MRP14, respectively) are Ca2 binding proteins belonging to the S100 family. They often exist in the form of heterodimer, while homodimer exists very little because of the stability. S100A8/A9 is constitutively expressed in neutrophils and monocytes as a Ca2 sensor, participating in cytoskeleton rearrangement and arachidonic acid metabolism.
Z05796
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Product Introduction
Species Human
Protein Construction
S100A8 (Met1-Glu93)_x000D_
Accession # P05109		 His
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
> 95% as determined by HPLC
Endotoxin Level Less than 1EU per μg by the LAL method.
Expression System E.coli
Theoretical Molecular Weight 11.7 kDa
Apparent Molecular Weight The protein has a predicted MW of 11.7 kDa same as Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS, 2mM DTT (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

Examples
  • S100A8, His, Human
    • S100A8, His, Human

    The purity of S100A8, His, Human is greater than 95% as determined by SEC-HPLC.

  • S100A8, His, Human
    • S100A8, His, Human

    S100A8, His, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.


Background
Target Background S100A8 and S100A9 (also known as MRP8 and MRP14, respectively) are Ca2 binding proteins belonging to the S100 family. They often exist in the form of heterodimer, while homodimer exists very little because of the stability. S100A8/A9 is constitutively expressed in neutrophils and monocytes as a Ca2 sensor, participating in cytoskeleton rearrangement and arachidonic acid metabolism.
Synonyms Calgranulin-A; CFAG; MRP-8; p8; CAGA; S100A8; 60B8AG; CGLA; CP-10; NIF; L1Ag; MA387; MIF

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.