PLAU/uPA (pro form), His, Human
PLAU/uPA (pro Form), His, Human

Immobilized Human PLAU, His Tag at 0.5 μg/ml (100 μl/well) on the plate. Dose response curve for PLAU/uPA (pro form), His, Human, hFc Tag with the EC50 of 2.4ng/ml determined by ELISA.

PLAU/uPA (pro Form), His, Human

The purity of PLAU/uPA (pro form), His, Human is greater than 95% as determined by SEC-HPLC.

PLAU/uPA (pro Form), His, Human

PLAU/uPA (pro form), His, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

PLAU/uPA (pro form), His, Human

Plasminogen activator, urokinase (uPA) is a secreted serine protease whose Dysregulation is often accompanied by various cancers. PLAU inhibition could suppress tumor growth. Collectively, PLAU is necessary for tumor progression and can be a diagnostic and prognostic biomarker in HNSCC.
Z05759
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Product Introduction
Species Human
Protein Construction
PLAU/uPA (pro form) (Ser21-Leu431)_x000D_
Accession # P00749-1		 His
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA. Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 47.5 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 52-60 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in 25mM HEPES, 150mM NaCl (pH 7.5).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.

Examples
  • PLAU/uPA (pro Form), His, Human
    • PLAU/uPA (pro Form), His, Human

    Immobilized Human PLAU, His Tag at 0.5 μg/ml (100 μl/well) on the plate. Dose response curve for PLAU/uPA (pro form), His, Human, hFc Tag with the EC50 of 2.4ng/ml determined by ELISA.

  • PLAU/uPA (pro Form), His, Human
    • PLAU/uPA (pro Form), His, Human

    The purity of PLAU/uPA (pro form), His, Human is greater than 95% as determined by SEC-HPLC.

  • PLAU/uPA (pro Form), His, Human
    • PLAU/uPA (pro Form), His, Human

    PLAU/uPA (pro form), His, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.


Background
Target Background Plasminogen activator, urokinase (uPA) is a secreted serine protease whose Dysregulation is often accompanied by various cancers. PLAU inhibition could suppress tumor growth. Collectively, PLAU is necessary for tumor progression and can be a diagnostic and prognostic biomarker in HNSCC.
Synonyms PLAU; Urokinase; ATF; UPA; URK; u-PA; BDPLT5; QPD

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.