NPR1/NPRA mFc Chimera, Human
NPR1/NPRA MFc Chimera, Human

Immobilized NPR1/NPRA mFc Chimera, Human, mFc Tag at 5 μg/ml (100 μl/well) on the plate. Dose response curve for Anti-NPR1 Antibody, hFc Tag with the EC50 of 40.0 ng/ml determined by ELISA.

NPR1/NPRA MFc Chimera, Human

The purity of NPR1/NPRA mFc Chimera, Human is greater than 90% as determined by SEC-HPLC.

NPR1/NPRA MFc Chimera, Human

NPR1/NPRA mFc Chimera, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

NPR1/NPRA MFc Chimera, Human

Loaded NPR1/NPRA mFc Chimera, Human, mFc Tag on Anti-Mouse IgG Fc-Biosensor can bind Anti-NPR1 Antibody, hFc-Avi Tag with an affinity constant of 1.20 nM as determined in BLI assay (Gator® Prime).

NPR1/NPRA MFc Chimera, Human

Immobilized NPR1/NPRA mFc Chimera, Human, mFc Tag at 5 μg/ml (100 μl/well) on the plate. Dose response curve for Anti-NPR1 Antibody, hFc Tag with the EC50 of 40.0ng/ml determined by ELISA.

NPR1/NPRA mFc Chimera, Human

NPR1 (natriuretic peptide receptor 1), a receptor of ANP (atrial natriuretic peptide) whitch acting through NPR1, provokes hypotension. NPR1 was abundantly expressed in endothelial cells and smooth muscle cells of small arteries and arterioles. NPR1 plays a crucial role in ANP-mediated blood pressure regulation, presumably by a mechanism that is RGS2-dependent in the acute phase and RGS2-independent in the chronic phase.
Z05707
¥80,213.00

Ask us a question
Product Introduction
Species Human
Protein Construction
NPR1/NPRA (Gly33-Glu473)_x000D_
Accession # NP_000897.3		 mFc (IgG1)
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA. Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 74.56 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 80-110 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.

Examples
  • NPR1/NPRA MFc Chimera, Human
    • NPR1/NPRA MFc Chimera, Human

    Immobilized NPR1/NPRA mFc Chimera, Human, mFc Tag at 5 μg/ml (100 μl/well) on the plate. Dose response curve for Anti-NPR1 Antibody, hFc Tag with the EC50 of 40.0 ng/ml determined by ELISA.

  • NPR1/NPRA MFc Chimera, Human
    • NPR1/NPRA MFc Chimera, Human

    The purity of NPR1/NPRA mFc Chimera, Human is greater than 90% as determined by SEC-HPLC.

  • NPR1/NPRA MFc Chimera, Human
    • NPR1/NPRA MFc Chimera, Human

    NPR1/NPRA mFc Chimera, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

  • NPR1/NPRA MFc Chimera, Human
    • NPR1/NPRA MFc Chimera, Human

    Loaded NPR1/NPRA mFc Chimera, Human, mFc Tag on Anti-Mouse IgG Fc-Biosensor can bind Anti-NPR1 Antibody, hFc-Avi Tag with an affinity constant of 1.20 nM as determined in BLI assay (Gator® Prime).

  • NPR1/NPRA MFc Chimera, Human
    • NPR1/NPRA MFc Chimera, Human

    Immobilized NPR1/NPRA mFc Chimera, Human, mFc Tag at 5 μg/ml (100 μl/well) on the plate. Dose response curve for Anti-NPR1 Antibody, hFc Tag with the EC50 of 40.0ng/ml determined by ELISA.


Background
Target Background NPR1 (natriuretic peptide receptor 1), a receptor of ANP (atrial natriuretic peptide) whitch acting through NPR1, provokes hypotension. NPR1 was abundantly expressed in endothelial cells and smooth muscle cells of small arteries and arterioles. NPR1 plays a crucial role in ANP-mediated blood pressure regulation, presumably by a mechanism that is RGS2-dependent in the acute phase and RGS2-independent in the chronic phase.
Synonyms ANP-A; ANPR-A; NPR-A; GC-A; ANPRA

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.