NMNAT1, His, Human
NMNAT1, His, Human

NMNAT1, His, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

NMNAT1, His, Human

As a first line of defense, natural killer (NK) cells play a crucial role in the fight against infections.The presented study is the first of its kind that ascribes CD56dimCD16 NKG2C-expressing NK cells a crucial role in biasing adaptive immune responses upon influenza vaccination and suggests NKG2C as a potential biomarker in predicting pandemic influenza vaccine responsiveness.
Z05698
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Product Introduction
Species Human
Protein Construction
NMNAT1(Met1-Thr279)
Accession # Q9HAN9		 His
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
> 90% as determined by HPLC
Endotoxin Level Less than 1EU per μg by the LAL method.
Expression System Baculovirus-Insect Cells(Sf9)
Theoretical Molecular Weight 33.46 kDa
Apparent Molecular Weight The protein has a predicted MW of 33.46 kDa same as Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in 20mM Tris, 500mM NaCl, 3mM DTT (pH 7.5).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

Examples
  • NMNAT1, His, Human
    • NMNAT1, His, Human

    NMNAT1, His, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.


Background
Target Background Nicotinamide mononucleotide adenylyltransferease (NMNAT), a rate-limiting enzyme present in all organisms, reversibly catalyzes the important step in the biosynthesis of NAD from ATP and NMN. NMNAT also catalyzes the metabolic conversion of potent antitumor prodrugs like tiazofurin and benzamide riboside to their active forms which are analogs of NAD.
Synonyms NMNAT; LCA9; PNAT1

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.