Neogenin hFc Chimera, Human

Neogenin hFc Chimera, Human

Neogenin is a multifunctional transmembrane receptor belonging to the immunoglobulin superfamily. It displays identical secondary structure to deleted in colorectal cancer (DCC), a netrin receptor that is involved in axon guidance and cell survival.
Z05676
¥72,752.00

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Product Introduction
Species Human
Protein Construction
Neogenin (Ala34-Leu1105)_x000D_
Accession # Q92859-1		 hFc
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
> 95% as determined by HPLC
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA. Immobilized Human RGMa, His Tag at 5μg/ml (100μl/Well) on the plate can bind Neogenin hFc Chimera, Human. Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 144.37 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 150-180 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

Background
Target Background Neogenin is a multifunctional transmembrane receptor belonging to the immunoglobulin superfamily. It displays identical secondary structure to deleted in colorectal cancer (DCC), a netrin receptor that is involved in axon guidance and cell survival.
Synonyms NEO1; IGDCC2; NGN; NEO; neogenin 1;

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.