N Cadherin hFc Chimera, Human
N Cadherin HFc Chimera, Human

N Cadherin hFc Chimera, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 90%.

N Cadherin hFc Chimera, Human

Neural (N)-cadherin is a calcium-dependent single-chain transmembrane glycoprotein that mediates homotypic and heterotypic cell-cell adhesion. As an important member of the cadherin family, N-cadherin plays an important role in the developmental and functional regulation of the nervous system, brain, heart, skeletal muscles, blood vessels and hematopoietic microenvironment.
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Product Introduction
Species Human
Protein Construction
N Cadherin (Asp160-Ala724)_x000D_
Accession # NP_001783.2		 hFc
N-term C-term
Purity > 90% as determined by Bis-Tris PAGE
Endotoxin Level Less than 1EU per μg by the LAL method.
Expression System HEK293
Theoretical Molecular Weight 88.56 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 100-120 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

Examples
  • N Cadherin HFc Chimera, Human
    • N Cadherin HFc Chimera, Human

    N Cadherin hFc Chimera, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 90%.


Background
Target Background Neural (N)-cadherin is a calcium-dependent single-chain transmembrane glycoprotein that mediates homotypic and heterotypic cell-cell adhesion. As an important member of the cadherin family, N-cadherin plays an important role in the developmental and functional regulation of the nervous system, brain, heart, skeletal muscles, blood vessels and hematopoietic microenvironment.
Synonyms CDH2; N-cadherin; Neural cadherin; CD325; CDHN; CDw325; NCAD;

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.