MSPR/Ron, His, Human
MSPR/Ron, His, Human

MSPR/Ron, His, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

MSPR/Ron, His, Human

Macrophage-stimulating protein (MSP) is a serum protein belonging to the plasminogen-related growth factor family. The specific receptor for MSP is the RON (recepteur d'origine nantais) receptor tyrosine kinase - a member of the MET proto-oncogene family. Activation of RON by MSP exerts dual functions on macrophages.
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Product Introduction
Species Human
Protein Construction
MSPR/Ron (Glu25-Leu571)_x000D_
Accession # CAA49634.1		 His
N-term C-term
Purity > 95% as determined by Bis-Tris PAGE
Endotoxin Level Less than 1EU per μg by the LAL method.
Expression System HEK293
Theoretical Molecular Weight 59.71 kDa
Apparent Molecular Weight Due to furin cleavage, the protein migrates to 70-80 kDa (full length) and 40-50 kDa (alpha chain) and 35-40 kDa (partial beta chain) based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

Examples
  • MSPR/Ron, His, Human
    • MSPR/Ron, His, Human

    MSPR/Ron, His, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.


Background
Target Background Macrophage-stimulating protein (MSP) is a serum protein belonging to the plasminogen-related growth factor family. The specific receptor for MSP is the RON (recepteur d'origine nantais) receptor tyrosine kinase - a member of the MET proto-oncogene family. Activation of RON by MSP exerts dual functions on macrophages.
Synonyms MSP receptor; CDw136; p185-Ron; CD136; MSP R; MSP receptor; MSPR; MST1R; PTK8; RON

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.