MIF, His, Human
MIF, His, Human

MIF, His, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

MIF, His, Human

Macrophage migration inhibitory factor (MIF) is a pleiotropic cytokine with chemokine-like functions that increasingly is being studied in different aspects of cardiovascular disease. MIF was first identified as a proinflammatory and pro-survival mediator within the immune system, and a second structurally related MIF family member, D-dopachrome tautomerase (a.k.a. MIF-2), was reported recently.
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Product Introduction
Species Human
Protein Construction
MIF (Pro2-Ala115)_x000D_
Accession # P14174		 His
N-term C-term
Purity > 95% as determined by Bis-Tris PAGE
Endotoxin Level Less than 1EU per μg by the LAL method.
Expression System HEK293
Theoretical Molecular Weight 13.44 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 25-30 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

Examples
  • MIF, His, Human
    • MIF, His, Human

    MIF, His, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.


Background
Target Background Macrophage migration inhibitory factor (MIF) is a pleiotropic cytokine with chemokine-like functions that increasingly is being studied in different aspects of cardiovascular disease. MIF was first identified as a proinflammatory and pro-survival mediator within the immune system, and a second structurally related MIF family member, D-dopachrome tautomerase (a.k.a. MIF-2), was reported recently.
Synonyms GIF; L-dopachrome isomerase; GLIF; MMIF; EC 5.3.2.1; EC 5.3.3.12

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.