MICA, His & Avi, Human
MICA, His & Avi, Human

Immobilized MICA, His & Avi, Human, His Tag at 1μg/ml (100μl/well) on the plate. Dose response curve for Human NKG2D, hFc Tag with the EC50 of 0.63μg/ml determined by ELISA.

MICA, His & Avi, Human

Immobilized MICA, His & Avi, Human at 5μg/ml(100μl/well) on the plate. Dose response curve for Anti-MICA Antibody, hFc Tag with the EC50 of 0.16μg/ml determined by ELISA.

MICA, His & Avi, Human

The purity of MICA, His & Avi, Human is greater than 95% as determined by SEC-HPLC.

MICA, His & Avi, Human

MICA, His & Avi, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

MICA, His & Avi, Human

MICA (MHC class I chain-related gene A) is a transmembrane glycoprotein that functions as a ligand for human NKG2D. A closely related protein, MICB, shares 85% amino acid identity with MICA. These proteins are distantly related to the MHC class I proteins. They possess three extracellular Ig‑like domains, but they have no capacity to bind peptide or interact with beta 2-microglobulin..
Z05649
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Product Introduction
Species Human
Protein Construction
MICA (Glu24-Gln308)_x000D_
Accession # Q96QC4		 His Avi
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA. Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 35.8 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 55-70 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.

Examples
  • MICA, His & Avi, Human
    • MICA, His & Avi, Human

    Immobilized MICA, His & Avi, Human, His Tag at 1μg/ml (100μl/well) on the plate. Dose response curve for Human NKG2D, hFc Tag with the EC50 of 0.63μg/ml determined by ELISA.

  • MICA, His & Avi, Human
    • MICA, His & Avi, Human

    Immobilized MICA, His & Avi, Human at 5μg/ml(100μl/well) on the plate. Dose response curve for Anti-MICA Antibody, hFc Tag with the EC50 of 0.16μg/ml determined by ELISA.

  • MICA, His & Avi, Human
    • MICA, His & Avi, Human

    The purity of MICA, His & Avi, Human is greater than 95% as determined by SEC-HPLC.

  • MICA, His & Avi, Human
    • MICA, His & Avi, Human

    MICA, His & Avi, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.


Background
Target Background MICA (MHC class I chain-related gene A) is a transmembrane glycoprotein that functions as a ligand for human NKG2D. A closely related protein, MICB, shares 85% amino acid identity with MICA. These proteins are distantly related to the MHC class I proteins. They possess three extracellular Ig‑like domains, but they have no capacity to bind peptide or interact with beta 2-microglobulin..
Synonyms FLJ60820; MGC111087; MICA; PERB11.1; DAMA-345G11.2; FLJ36918; FLJ60820; MGC21250

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.