MICA alpha 3 mFc Chimera, Human
MICA Alpha 3 MFc Chimera, Human

Immobilized MICA alpha 3 mFc Chimera, Human, mFc Tag at 2 μg/ml (100 μl/well) on the plate. Dose response curve for Anti-MICA Antibody, hFc Tag with the EC50 of 0.11 μg/ml determined by ELISA.

MICA Alpha 3 MFc Chimera, Human

The purity of MICA alpha 3 mFc Chimera, Human 3 is greater than 95% as determined by SEC-HPLC.

MICA Alpha 3 MFc Chimera, Human

MICA alpha 3 mFc Chimera, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

MICA alpha 3 mFc Chimera, Human

MICA (MHC class I chain-related gene A) is a transmembrane glycoprotein that functions as a ligand for human NKG2D. A closely related protein, MICB, shares 85% amino acid identity with MICA. These proteins are distantly related to the MHC class I proteins. They possess three extracellular Ig‑like domains, but they have no capacity to bind peptide or interact with beta 2-microglobulin.
Z05647
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Product Introduction
Species Human
Protein Construction
mFc (IgG1) MICA alpha 3 (Arg105-Ser200)
Accession # NP_001276081.1
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA. Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 36.8 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 50-65 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.

Examples
  • MICA Alpha 3 MFc Chimera, Human
    • MICA Alpha 3 MFc Chimera, Human

    Immobilized MICA alpha 3 mFc Chimera, Human, mFc Tag at 2 μg/ml (100 μl/well) on the plate. Dose response curve for Anti-MICA Antibody, hFc Tag with the EC50 of 0.11 μg/ml determined by ELISA.

  • MICA Alpha 3 MFc Chimera, Human
    • MICA Alpha 3 MFc Chimera, Human

    The purity of MICA alpha 3 mFc Chimera, Human 3 is greater than 95% as determined by SEC-HPLC.

  • MICA Alpha 3 MFc Chimera, Human
    • MICA Alpha 3 MFc Chimera, Human

    MICA alpha 3 mFc Chimera, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.


Background
Target Background MICA (MHC class I chain-related gene A) is a transmembrane glycoprotein that functions as a ligand for human NKG2D. A closely related protein, MICB, shares 85% amino acid identity with MICA. These proteins are distantly related to the MHC class I proteins. They possess three extracellular Ig‑like domains, but they have no capacity to bind peptide or interact with beta 2-microglobulin.
Synonyms MICA; MIC-A; MICA alpha 3

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.