MERTK/Mer, His, Human
MERTK/Mer, His, Human

The purity of MERTK/Mer, His, Human is greater than 95% as determined by SEC-HPLC.

MERTK/Mer, His, Human

MERTK/Mer, His, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

MERTK/Mer, His, Human

MER tyrosine kinase (MERTK) encodes a surface receptor localized at the apical membrane of the retinal pigment epithelium. It plays a critical role in photoreceptor outer segment internalization prior to phagocytosis. Mutations in MERTK have been associated with severe autosomal recessive retinal dystrophies in the RCS rat and in humans.
Z05643
¥63,425.00

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Product Introduction
Species Human
Protein Construction
MERTK/Mer (Ala21-Ile505)_x000D_
Accession # Q12866-1		 His
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
> 95% as determined by HPLC
Endotoxin Level Less than 1EU per μg by the LAL method.
Expression System HEK293
Theoretical Molecular Weight 53.73 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 95-115 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

Examples
  • MERTK/Mer, His, Human
    • MERTK/Mer, His, Human

    The purity of MERTK/Mer, His, Human is greater than 95% as determined by SEC-HPLC.

  • MERTK/Mer, His, Human
    • MERTK/Mer, His, Human

    MERTK/Mer, His, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.


Background
Target Background MER tyrosine kinase (MERTK) encodes a surface receptor localized at the apical membrane of the retinal pigment epithelium. It plays a critical role in photoreceptor outer segment internalization prior to phagocytosis. Mutations in MERTK have been associated with severe autosomal recessive retinal dystrophies in the RCS rat and in humans.
Synonyms MERTK; MER; c-Eyk; MGC133349; c-mer; RP38; Tyro12

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.