MASP3, His, Human
MASP3, His, Human

The purity of MASP3, His, Human is greater than 95% as determined by SEC-HPLC.

MASP3, His, Human

MASP3, His, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

MASP3, His, Human

Mannose-binding lectin-associated serine protease-1 (also named MASP3), a multifunctional serine protease, plays an important role in innate immunity which is capable of activating the lectin pathway of the complement system and also triggering coagulation cascade system.
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Product Introduction
Species Human
Protein Construction
MASP3 (Ile450-Val721)_x000D_
Accession # P48740-2		 His
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE
> 95% as determined by HPLC
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its ability to cleave a colorimetric peptide substrate, N­carbobenzyloxy­LysThioBenzyl ester (Z­Lys­SBzl), in the presence of 5,5'Dithio­bis (2­nitrobenzoic acid) (DTNB). The specific activity is > 10000 pmol/min/µg. Test result meets the standard.
Expression System HEK293
Theoretical Molecular Weight 31.10 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 43-53 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

Examples
  • MASP3, His, Human
    • MASP3, His, Human

    The purity of MASP3, His, Human is greater than 95% as determined by SEC-HPLC.

  • MASP3, His, Human
    • MASP3, His, Human

    MASP3, His, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.


Background
Target Background Mannose-binding lectin-associated serine protease-1 (also named MASP3), a multifunctional serine protease, plays an important role in innate immunity which is capable of activating the lectin pathway of the complement system and also triggering coagulation cascade system.
Synonyms MASP-3; MASP-1; MASP1; RaRF; Serine protease 5; CRARF; CRARF1; PRSS5;

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.