MADCAM1 hFc Chimera, Human
MADCAM1 HFc Chimera, Human

Immobilized MADCAM1 hFc Chimera, Human, hFc Tag at 1 μg /ml(100 μl/well) on the plate. Dose response curve for Biotinylated Anti-MADCAM1 Antibody, hFc Tag with the EC50 of 16.6ng/ml determined by ELISA.

MADCAM1 HFc Chimera, Human

Immobilized Human ITGA4&ITGB7, His Tag at 5 μg /ml (100 μl/well) on the plate. Dose response curve for MADCAM1 hFc Chimera, Human, hFc Tag with the EC50 of 5.5 μg /ml determined by ELISA.

MADCAM1 HFc Chimera, Human

The purity of MADCAM1 hFc Chimera, Human is greater than 95% as determined by SEC-HPLC.

MADCAM1 HFc Chimera, Human

MADCAM1 hFc Chimera, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%

MADCAM1 hFc Chimera, Human

Mucosal addressin cell adhesion molecule-1 (MAdCAM-1) contributes to the recruitment of donor T cells into the mucosal tissues of the recipient after allogeneic hematopoietic stem cell transplantation (aHSCT). The aim of our study was to determine whether selected single nucleotide polymorphisms (SNPs) of the MADCAM1 gene are associated with development of serious complications after aHSCT.
Z05623
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Product Introduction
Species Human
Protein Construction
MADCAM1 (Gln19-Gln317)
Accession # Q13477-1		 hFc
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA. Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 58.17 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 75-95 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.

Examples
  • MADCAM1 HFc Chimera, Human
    • MADCAM1 HFc Chimera, Human

    Immobilized MADCAM1 hFc Chimera, Human, hFc Tag at 1 μg /ml(100 μl/well) on the plate. Dose response curve for Biotinylated Anti-MADCAM1 Antibody, hFc Tag with the EC50 of 16.6ng/ml determined by ELISA.

  • MADCAM1 HFc Chimera, Human
    • MADCAM1 HFc Chimera, Human

    Immobilized Human ITGA4&ITGB7, His Tag at 5 μg /ml (100 μl/well) on the plate. Dose response curve for MADCAM1 hFc Chimera, Human, hFc Tag with the EC50 of 5.5 μg /ml determined by ELISA.

  • MADCAM1 HFc Chimera, Human
    • MADCAM1 HFc Chimera, Human

    The purity of MADCAM1 hFc Chimera, Human is greater than 95% as determined by SEC-HPLC.

  • MADCAM1 HFc Chimera, Human
    • MADCAM1 HFc Chimera, Human

    MADCAM1 hFc Chimera, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%


Background
Target Background Mucosal addressin cell adhesion molecule-1 (MAdCAM-1) contributes to the recruitment of donor T cells into the mucosal tissues of the recipient after allogeneic hematopoietic stem cell transplantation (aHSCT). The aim of our study was to determine whether selected single nucleotide polymorphisms (SNPs) of the MADCAM1 gene are associated with development of serious complications after aHSCT.
Synonyms MAdCAM-1; MADCAM1; MACAM1

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.