LIGHT/TNFSF14 hFc Chimera, Human

LIGHT/TNFSF14 hFc Chimera, Human

LIGHT, also known as tumor necrosis factor superfamily member 14 (TNFSF14), is a secreted protein of the TNF superfamily. It is recognized by herpesvirus entry mediator (HVEM), as well as decoy receptor 3.This protein has been shown to stimulate the proliferation of T cells, and trigger apoptosis of various tumor cells.
Z05582
¥69,021.00

Ask us a question
Product Introduction
Species Human
Protein Construction
hFc LIGHT/TNFSF14 (Asp74-Val240)_x000D_
Accession # O43557-1
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
> 95% as determined by HPLC
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA. Immobilized Human HVEM, His Tag at 1μg/ml (100μl/Well) on the plate can bind LIGHT/TNFSF14 hFc Chimera, Human. Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 45.5 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 53-60 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

Background
Target Background LIGHT, also known as tumor necrosis factor superfamily member 14 (TNFSF14), is a secreted protein of the TNF superfamily. It is recognized by herpesvirus entry mediator (HVEM), as well as decoy receptor 3.This protein has been shown to stimulate the proliferation of T cells, and trigger apoptosis of various tumor cells.
Synonyms CD258; TNFSF14; HVEM-L; LIGHT; LTg; TR2

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.