LDLR, His & Avi, Human
LDLR, His & Avi, Human

The purity of LDLR, His & Avi, Human is greater than 95% as determined by SEC-HPLC.

LDLR, His & Avi, Human

LDLR, His & Avi, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

LDLR, His & Avi, Human

LDLR, His & Avi, Human, His Tag immobilized on CM5 Chip can bind Human PCSK9, His Tag with an affinity constant of 0.35 nM as determined in SPR assay (Biacore T200).

LDLR, His & Avi, Human

The low density lipoprotein receptor (LDLR) is the founding member of the LDL R family of widely expressed cell surface scavenger receptors. It is a cell-surface receptor that recognizes the apoprotein B100 which is embedded in the phospholipid outer layer of LDL particles.
Z05571
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Product Introduction
Species Human
Protein Construction
LDLR (Ala22-Arg788)_x000D_
Accession # P01130-1		 His Avi
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
> 95% as determined by HPLC
Endotoxin Level Less than 1EU per μg by the LAL method.
Expression System HEK293
Theoretical Molecular Weight 87.6 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 110-130 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

Examples
  • LDLR, His & Avi, Human
    • LDLR, His & Avi, Human

    The purity of LDLR, His & Avi, Human is greater than 95% as determined by SEC-HPLC.

  • LDLR, His & Avi, Human
    • LDLR, His & Avi, Human

    LDLR, His & Avi, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

  • LDLR, His & Avi, Human
    • LDLR, His & Avi, Human

    LDLR, His & Avi, Human, His Tag immobilized on CM5 Chip can bind Human PCSK9, His Tag with an affinity constant of 0.35 nM as determined in SPR assay (Biacore T200).


Background
Target Background The low density lipoprotein receptor (LDLR) is the founding member of the LDL R family of widely expressed cell surface scavenger receptors. It is a cell-surface receptor that recognizes the apoprotein B100 which is embedded in the phospholipid outer layer of LDL particles.
Synonyms LDLR; FHC; LDL R; LDL receptor; LDLCQ2; FH

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.