LAYN, His, Human
LAYN, His, Human

The purity of LAYN, His, Human is greater than 95% as determined by SEC-HPLC

LAYN, His, Human

LAYN, His, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

LAYN, His, Human

Layilin (LAYN) is a critical gene that regulates T cell function. LAYN is correlated with prognosis and immune infiltrating levels of, including those of CD8 T cells, CD4 T cells, macrophages, neutrophils, and DCs in multiple cancers, especially in colon and gastric cancer patients. In addition, LAYN expression potentially contributes to regulation of tumor-associated macrophages (TAMs), DCs, T cell exhaustion and Tregs in colon and gastric cancer.
Z05569
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Product Introduction
Species Human
Protein Construction
LAYN (Ala22-Leu235)_x000D_
Accession # Q6UX15-2		 His
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
> 95% as determined by HPLC
Endotoxin Level Less than 1EU per μg by the LAL method.
Expression System HEK293
Theoretical Molecular Weight 25.4 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 35-42 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

Examples
  • LAYN, His, Human
    • LAYN, His, Human

    The purity of LAYN, His, Human is greater than 95% as determined by SEC-HPLC

  • LAYN, His, Human
    • LAYN, His, Human

    LAYN, His, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.


Background
Target Background Layilin (LAYN) is a critical gene that regulates T cell function. LAYN is correlated with prognosis and immune infiltrating levels of, including those of CD8 T cells, CD4 T cells, macrophages, neutrophils, and DCs in multiple cancers, especially in colon and gastric cancer patients. In addition, LAYN expression potentially contributes to regulation of tumor-associated macrophages (TAMs), DCs, T cell exhaustion and Tregs in colon and gastric cancer.
Synonyms Layilin; FLJ30977; FLJ31092; LAYN; LYAN

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.