LAMP5 hFc Chimera, Human
LAMP5 HFc Chimera, Human

The purity of LAMP5 hFc Chimera, Human is greater than 95% as determined by SEC-HPLC

LAMP5 HFc Chimera, Human

LAMP5 hFc Chimera, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

LAMP5 hFc Chimera, Human

Lysosome-associated membrane protein 5 (LAMP5) is a mammalian ortholog of the Caenorhabditis elegans protein, UNC-46, which functions as a sorting factor to localize the vesicular GABA transporter UNC-47 to synaptic vesicles. In the mouse forebrain, LAMP5 is expressed in a subpopulation of GABAergic neurons in the olfactory bulb and the striato-nigral system, where it is required for fine-tuning of GABAergic synaptic transmission.
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Product Introduction
Species Human
Protein Construction
LAMP5 (Glu30-Glu235)_x000D_
Accession # Q9UJQ1-1		 hFc
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
> 95% as determined by HPLC
Endotoxin Level Less than 1EU per μg by the LAL method.
Expression System HEK293
Theoretical Molecular Weight 49.8 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 60-70 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

Examples
  • LAMP5 HFc Chimera, Human
    • LAMP5 HFc Chimera, Human

    The purity of LAMP5 hFc Chimera, Human is greater than 95% as determined by SEC-HPLC

  • LAMP5 HFc Chimera, Human
    • LAMP5 HFc Chimera, Human

    LAMP5 hFc Chimera, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.


Background
Target Background Lysosome-associated membrane protein 5 (LAMP5) is a mammalian ortholog of the Caenorhabditis elegans protein, UNC-46, which functions as a sorting factor to localize the vesicular GABA transporter UNC-47 to synaptic vesicles. In the mouse forebrain, LAMP5 is expressed in a subpopulation of GABAergic neurons in the olfactory bulb and the striato-nigral system, where it is required for fine-tuning of GABAergic synaptic transmission.
Synonyms BAD-LAMP; LAMP-5; BADLAMP; C20orf103; dJ1119D9.3; UNC-43

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.