IL-1 alpha/IL-1A, Human
IL-1 Alpha/IL-1A, Human

The purity of IL-1 alpha/IL-1A, Human is greater than 95% as determined by SEC-HPLC.

IL-1 Alpha/IL-1A, Human

IL-1 alpha/IL-1A, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

IL-1 Alpha/IL-1A, Human

Human IL-1R1, His Tag captured on CM5 Chip via anti-his antibody can bind IL-1 alpha/IL-1A, Human, No tag with an affinity constant of 0.51 nM as determined in SPR assay (Biacore T200).

IL-1 alpha/IL-1A, Human

The interleukin (IL)-1 family of cytokines is currently comprised of 11 members that have pleiotropic functions in inflammation and cancer. IL-1α and IL-1β were the first members of the IL-1 family to be described, and both signal via the same receptor, IL-1R. Over the last decade, much progress has been made in our understanding of biogenesis of IL-1β and its functions in human diseases.
Z05418
¥72,752.00

Ask us a question
Product Introduction
Species Human
Protein Construction
IL-1 alpha/IL-1A (Ser113-Ala271)
Accession # NP_000566.3
Purity > 95% as determined by Bis­Tris PAGE 
> 95% as determined by HPLC
Endotoxin Level Less than 0.05EU per μg by the LAL method.
Biological Activity Human IL­1R1, His Tag captured on CM5 Chip via anti­his antibody can bind IL-1 alpha/IL-1A, Human in SPR assay (Biacore T200). Test result was comparable to standard batch.
Expression System E.coli
Theoretical Molecular Weight 18 kDa
Apparent Molecular Weight The protein has a predicted MW of 18 kDa same as Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

Examples
  • IL-1 Alpha/IL-1A, Human
  • IL-1 Alpha/IL-1A, Human

    The purity of IL-1 alpha/IL-1A, Human is greater than 95% as determined by SEC-HPLC.

  • IL-1 Alpha/IL-1A, Human
  • IL-1 Alpha/IL-1A, Human

    IL-1 alpha/IL-1A, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

  • IL-1 Alpha/IL-1A, Human
  • IL-1 Alpha/IL-1A, Human

    Human IL-1R1, His Tag captured on CM5 Chip via anti-his antibody can bind IL-1 alpha/IL-1A, Human, No tag with an affinity constant of 0.51 nM as determined in SPR assay (Biacore T200).


Background
Target Background The interleukin (IL)-1 family of cytokines is currently comprised of 11 members that have pleiotropic functions in inflammation and cancer. IL-1α and IL-1β were the first members of the IL-1 family to be described, and both signal via the same receptor, IL-1R. Over the last decade, much progress has been made in our understanding of biogenesis of IL-1β and its functions in human diseases.
Synonyms Interleukin-1 alpha; IL-1 alpha; Hematopoietin-1; IL1A; IL1F1; IL-1 ALPHA; IL1α; IL-1A; IL1

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.