IGFBP-7 hFc Chimera, Human
IGFBP-7 HFc Chimera, Human

Immobilized Human CD93, His Tag at 5 μg/ml (100 μl/well) on the plate. Dose response curve for IGFBP-7 hFc Chimera, Human, hFc Tag with the EC50 of 0.40 μg/ml determined by ELISA.

IGFBP-7 HFc Chimera, Human

The purity of IGFBP-7 hFc Chimera, Human is greater than 95% as determined by SEC-HPLC.

IGFBP-7 HFc Chimera, Human

IGFBP-7 hFc Chimera, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

IGFBP-7 hFc Chimera, Human

IGFBP-7, also known as Mac25/Angiomodulin (AGM), GFBP-rp1, tumor-derived adhesion factor (TAF) and prostacyclin-stimulating factor (PSF), is a secreted protein that contains three protein domain modules. Human IGFBP-rp1 cDNA encodes 282 amino acid (aa) residue precursor protein with a putative 26 aa signal peptide. IGFBP-7 binds IGF-I and IGF-II with a relatively low affinity. Stimulates prostacyclin (PGI2) production. Stimulates cell adhesion.
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Product Introduction
Species Human
Protein Construction
IGFBP-7 (Ser27-Leu282)
Accession # Q16270		 hFc
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA. Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 53.20 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 60-70 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.

Examples
  • IGFBP-7 HFc Chimera, Human
    • IGFBP-7 HFc Chimera, Human

    Immobilized Human CD93, His Tag at 5 μg/ml (100 μl/well) on the plate. Dose response curve for IGFBP-7 hFc Chimera, Human, hFc Tag with the EC50 of 0.40 μg/ml determined by ELISA.

  • IGFBP-7 HFc Chimera, Human
    • IGFBP-7 HFc Chimera, Human

    The purity of IGFBP-7 hFc Chimera, Human is greater than 95% as determined by SEC-HPLC.

  • IGFBP-7 HFc Chimera, Human
    • IGFBP-7 HFc Chimera, Human

    IGFBP-7 hFc Chimera, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.


Background
Target Background IGFBP-7, also known as Mac25/Angiomodulin (AGM), GFBP-rp1, tumor-derived adhesion factor (TAF) and prostacyclin-stimulating factor (PSF), is a secreted protein that contains three protein domain modules. Human IGFBP-rp1 cDNA encodes 282 amino acid (aa) residue precursor protein with a putative 26 aa signal peptide. IGFBP-7 binds IGF-I and IGF-II with a relatively low affinity. Stimulates prostacyclin (PGI2) production. Stimulates cell adhesion.
Synonyms IGFBP-7; IBP7; AGM; FSTL2; IGFBP-7v; IGFBPRP1; MAC25; PSF; RAMSVPS; TAF

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.