HVEM/TNFRSF14 hFc Chimera, Human
HVEM/TNFRSF14 HFc Chimera, Human

Immobilized Human BTLA, His Tag at 1 μg/ml (100 μl/well) on the plate. Dose response curve for HVEM/TNFRSF14 hFc Chimera, Human, hFc Tag with the EC50 of 27.2 ng/ml determined by ELISA.

HVEM/TNFRSF14 HFc Chimera, Human

HVEM/TNFRSF14 hFc Chimera, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

HVEM/TNFRSF14 hFc Chimera, Human

Herpesvirus entry mediator (HVEM), also known as tumor necrosis factor receptor superfamily member 14 (TNFRSF14), is a human cell surface receptor of the TNF-receptor superfamily. Two TNF superfamily ligands lymphotoxin α (TNF-β) and LIGHT (TNFSF14) are identified as cellular ligands for HVEM and initiate the positive signaling.
Z05388
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Product Introduction
Species Human
Protein Construction
HVEM/TNFRSF14 (Leu39-Val202)
Accession # Q92956-1		 hFc
N-term C-term
Purity > 95% as determined by Bis-Tris PAGE
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA. Immobilized Human BTLA, His Tag at 1μg/ml (100 μl/Well) on the plate can bind HVEM/TNFRSF14 hFc Chimera, Human. Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 44.3 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 60-70 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

Examples
  • HVEM/TNFRSF14 HFc Chimera, Human
    • HVEM/TNFRSF14 HFc Chimera, Human

    Immobilized Human BTLA, His Tag at 1 μg/ml (100 μl/well) on the plate. Dose response curve for HVEM/TNFRSF14 hFc Chimera, Human, hFc Tag with the EC50 of 27.2 ng/ml determined by ELISA.

  • HVEM/TNFRSF14 HFc Chimera, Human
    • HVEM/TNFRSF14 HFc Chimera, Human

    HVEM/TNFRSF14 hFc Chimera, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.


Background
Target Background Herpesvirus entry mediator (HVEM), also known as tumor necrosis factor receptor superfamily member 14 (TNFRSF14), is a human cell surface receptor of the TNF-receptor superfamily. Two TNF superfamily ligands lymphotoxin α (TNF-β) and LIGHT (TNFSF14) are identified as cellular ligands for HVEM and initiate the positive signaling.
Synonyms CD270; CD40-like protein; HVEM; LIGHTR; ATAR; TNFRSF14; TR2

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.