GIP, His, Human
GIP, His, Human

Immobilized GIP, His, Human, His Tag at 1 μg /ml (100 μl/well) on the plate. Dose response curve for Anti-GIP Antibody, hFc Tag with the EC50 of 4.7ng/ml determined by ELISA.

GIP, His, Human

The purity of GIP, His, Human is greater than 95% as determined by SEC-HPLC.

GIP, His, Human

GIP, His, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

GIP, His, Human

The potential application of glucose-dependent insulinotropic polypeptide (gastric inhibitory polypeptide, GIP) in the management of obesity and type 2 diabetes has been controversial. Initial interest in the therapeutic use of GIP was dampened by evidence that its insulinotropic activity was reduced in type 2 diabetes and by reports that it increased glucagon secretion and adipose deposition in non-diabetic individuals.
Z05352
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Product Introduction
Species Human
Protein Construction
GIP (Glu22-Gln93)
Accession # P09681		 His
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA. Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 9.2 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 15-25 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.

Examples
  • GIP, His, Human
    • GIP, His, Human

    Immobilized GIP, His, Human, His Tag at 1 μg /ml (100 μl/well) on the plate. Dose response curve for Anti-GIP Antibody, hFc Tag with the EC50 of 4.7ng/ml determined by ELISA.

  • GIP, His, Human
    • GIP, His, Human

    The purity of GIP, His, Human is greater than 95% as determined by SEC-HPLC.

  • GIP, His, Human
    • GIP, His, Human

    GIP, His, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.


Background
Target Background The potential application of glucose-dependent insulinotropic polypeptide (gastric inhibitory polypeptide, GIP) in the management of obesity and type 2 diabetes has been controversial. Initial interest in the therapeutic use of GIP was dampened by evidence that its insulinotropic activity was reduced in type 2 diabetes and by reports that it increased glucagon secretion and adipose deposition in non-diabetic individuals.
Synonyms GIP; Incretin

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.