GGT1, His, Human
GGT1, His, Human

The purity of GGT1, His, Human is greater than 95% as determined by SEC-HPLC.

GGT1, His, Human

GGT1, His, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

GGT1, His, Human

Gamma-glutamyl transferase (GGT; EC 2.3.2.2) is the only enzyme capable of degrading glutathione (GSH) in extra-cytosolic spaces. Overexpression of γ-glutamyl transpeptidase (GGT1) has been implicated in an array of human diseases including asthma, reperfusion injury, and cancer.
Z05350
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Product Introduction
Species Human
Protein Construction
His GGT1 (Pro27-Tyr569)
Accession # P19440-1
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
> 95% as determined by HPLC
Endotoxin Level Less than 1EU per μg by the LAL method.
Expression System HEK293
Theoretical Molecular Weight 59.69 kDa
Apparent Molecular Weight Due to enzyme lysis and glycosylation, the protein migrates to 55-65 kDa (heavy chain) and 25-30 kDa (light chain) based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

Examples
  • GGT1, His, Human
  • GGT1, His, Human

    The purity of GGT1, His, Human is greater than 95% as determined by SEC-HPLC.

  • GGT1, His, Human
  • GGT1, His, Human

    GGT1, His, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.


Background
Target Background Gamma-glutamyl transferase (GGT; EC 2.3.2.2) is the only enzyme capable of degrading glutathione (GSH) in extra-cytosolic spaces. Overexpression of γ-glutamyl transpeptidase (GGT1) has been implicated in an array of human diseases including asthma, reperfusion injury, and cancer.
Synonyms Gamma-glutamyltransferase 1; GGT 1; CD224; GGT; GGT-1; GGTD; D22S672; D22S73; D22S732

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.