FLT3 Ligand hFc Chimera, Human

FLT3 Ligand hFc Chimera, Human

Flt‑3 Ligand, also known as FL, is an alpha -helical cytokine that promotes the differentiation of multiple hematopoietic cell lineages.Stimulates the proliferation of early hematopoietic cells by activating FLT3. Synergizes well with a number of other colony stimulating factors and interleukins.
Z05311
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Product Introduction
Species Human
Protein Construction
FLT3 Ligand (Thr27-Pro185)
Accession # P49771-1		 hFc
N-term C-term
Purity > 95% as determined by Bis-Tris PAGE
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA. Immobilized Human Human FLT3, His Tag at 0.5μg/ml (100μl/Well) on the plate can bind FLT3 Ligand hFc Chimera, Human. Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 44.8 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 90-118 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

Background
Target Background Flt‑3 Ligand, also known as FL, is an alpha -helical cytokine that promotes the differentiation of multiple hematopoietic cell lineages.Stimulates the proliferation of early hematopoietic cells by activating FLT3. Synergizes well with a number of other colony stimulating factors and interleukins.
Synonyms FL; Flt3 ligand; Flt3L; FLT3LG; SL cytokine

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.