FGF10, Human
FGF10, Human

FGF10, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

FGF10, Human

FGF10, Human, No Tag immobilized on CM5 Chip can bind Human FGFR2 beta (IIIb), hFc Tag with an affinity constant of 8.43 nM as determined in SPR assay (Biacore T200).

FGF10, Human

Affinity of FGFR2 (hc-tagged) captured on hFc probes with FGF10

FGF10, Human

Affinity of FGFR2 (his-tagged) captured on his probes with FGF10

FGF10, Human

Fibroblast growth factor 10 (FGF10) regulates multiple stages of structural lung morphogenesis, cellular differentiation, and the response to injury. As a driver of lung airway branching morphogenesis, FGF10 signaling defects during development lead to neonatal lung disease. Lung diseases impact patients across the lifespan, from infants in the first minutes of life through the aged population. Congenital abnormalities of lung structure can cause lung disease at birth or make adults more susceptible to chronic disease.
Z05289
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Product Introduction
Species Human
Protein Construction
FGF10 (Gln38-Ser208)
Accession # O15520
Purity > 90% as determined by Bis-Tris PAGE
Endotoxin Level Less than 0.1EU per μg by the LAL method.
Biological Activity FGF10, Human immobilized on CM5 Chip can bind Human FGFR2 beta (IIIb), hFc Tag in SPR assay (Biacore T200). Test result was comparable to standard batch.
Expression System E.coli
Theoretical Molecular Weight 19.3 kDa
Apparent Molecular Weight The protein migrates to 25 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in 20mM Tris, 150mM NaCl (pH 8.0).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.

Examples
  • FGF10, Human
    • FGF10, Human

    FGF10, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

  • FGF10, Human
    • FGF10, Human

    FGF10, Human, No Tag immobilized on CM5 Chip can bind Human FGFR2 beta (IIIb), hFc Tag with an affinity constant of 8.43 nM as determined in SPR assay (Biacore T200).

  • FGF10, Human
    • FGF10, Human

    Affinity of FGFR2 (hc-tagged) captured on hFc probes with FGF10

  • FGF10, Human
    • FGF10, Human

    Affinity of FGFR2 (his-tagged) captured on his probes with FGF10


Background
Target Background Fibroblast growth factor 10 (FGF10) regulates multiple stages of structural lung morphogenesis, cellular differentiation, and the response to injury. As a driver of lung airway branching morphogenesis, FGF10 signaling defects during development lead to neonatal lung disease. Lung diseases impact patients across the lifespan, from infants in the first minutes of life through the aged population. Congenital abnormalities of lung structure can cause lung disease at birth or make adults more susceptible to chronic disease.
Synonyms FGF-10; KGF2

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.