EphB4, His, Human
EphB4, His, Human

The purity of EphB4, His, Human is greater than 95% as determined by SEC-HPLC.

EphB4, His, Human

EphB4, His, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

EphB4, His, Human

The erythropoietin-producing hepatocellular carcinoma (Eph) receptors are the largest family of receptor tyrosine kinases (RTKs) that include two major subclasses, EphA and EphB. They form an important cell communication system with critical and diverse roles in a variety of biological processes during embryonic development. The emerging picture suggests that EphB4 is a valuable and attractive therapeutic target for upper aerodigestive malignancies.
Z05256
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Product Introduction
Species Human
Protein Construction
EphB4 (Leu16-Ala539)
Accession # NP_004435.3		 His
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
> 95% as determined by HPLC
Endotoxin Level Less than 1EU per μg by the LAL method.
Expression System HEK293
Theoretical Molecular Weight 58.2 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 60-70 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

Examples
  • EphB4, His, Human
    • EphB4, His, Human

    The purity of EphB4, His, Human is greater than 95% as determined by SEC-HPLC.

  • EphB4, His, Human
    • EphB4, His, Human

    EphB4, His, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.


Background
Target Background The erythropoietin-producing hepatocellular carcinoma (Eph) receptors are the largest family of receptor tyrosine kinases (RTKs) that include two major subclasses, EphA and EphB. They form an important cell communication system with critical and diverse roles in a variety of biological processes during embryonic development. The emerging picture suggests that EphB4 is a valuable and attractive therapeutic target for upper aerodigestive malignancies.
Synonyms EPHB4; HTK; MYK1; TYRO11

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.