DKK3, His & Avi, Human
DKK3, His & Avi, Human

The purity of DKK3, His & Avi, Human is greater than 95% as determined by SEC-HPLC.

DKK3, His & Avi, Human

DKK3, His & Avi, Human on Bis-Tris PAGE under reduced conditions. The purity is greater than 95%.

DKK3, His & Avi, Human

Dkk-3, also known as REIC (Reduced Expansion in Immortalized Cells), is one of four numbered members of the Dickkopf family of Wnt antagonists.DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.
Z05220
¥63,425.00

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Product Introduction
Species Human
Protein Construction
DKK3 (Pro23-Ile350)
Accession # Q9UBP4		 His Avi
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
> 95% as determined by HPLC
Endotoxin Level Less than 1EU per μg by the LAL method.
Expression System HEK293
Theoretical Molecular Weight 39.5 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 55-70 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

Examples
  • DKK3, His & Avi, Human
    • DKK3, His & Avi, Human

    The purity of DKK3, His & Avi, Human is greater than 95% as determined by SEC-HPLC.

  • DKK3, His & Avi, Human
    • DKK3, His & Avi, Human

    DKK3, His & Avi, Human on Bis-Tris PAGE under reduced conditions. The purity is greater than 95%.


Background
Target Background Dkk-3, also known as REIC (Reduced Expansion in Immortalized Cells), is one of four numbered members of the Dickkopf family of Wnt antagonists.DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.
Synonyms Dickkopf-3; Dkk3; REIC; REICdkk-3; RIG; RIG-like 5-6; RIG-like 7-1; AW061014; C87148

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.