CPM, His, Human
CPM, His, Human

The purity of CPM, His, Human is greater than 95% as determined by SEC-HPLC.

CPM, His, Human

CPM, His, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%

CPM, His, Human

Carboxypeptidase M (CPM) is a glycosylphosphatidylinositol anchored enzyme that plays an important role in the kallikrein-kinin system (KKS). CPM catalytic domain hydrolyzes Arg from C-terminal peptides (i.e., bradykinin and kallidin), generating des-Arg-kinins, the agonists of B1 receptor (B1R).
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Product Introduction
Species Human
Protein Construction
CPM (Leu18-Ser423)
Accession # P14384		 His
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
Endotoxin Level Less than 1EU per μg by the LAL method.
Expression System HEK293
Theoretical Molecular Weight 47.48 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 50-65 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.

Examples
  • CPM, His, Human
    • CPM, His, Human

    The purity of CPM, His, Human is greater than 95% as determined by SEC-HPLC.

  • CPM, His, Human
    • CPM, His, Human

    CPM, His, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%


Background
Target Background Carboxypeptidase M (CPM) is a glycosylphosphatidylinositol anchored enzyme that plays an important role in the kallikrein-kinin system (KKS). CPM catalytic domain hydrolyzes Arg from C-terminal peptides (i.e., bradykinin and kallidin), generating des-Arg-kinins, the agonists of B1 receptor (B1R).
Synonyms Carboxypeptidase M; 1110060I01Rik; AA589379

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.