Complement C3, His, Human
Complement C3, His, Human

The purity of Complement C3, His, Human is greater than 95% as determined by SEC-HPLC.

Complement C3, His, Human

Complement C3, His, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

Complement C3, His, Human

Complement component 3 (C3), a pivotal molecule in the complement system, is an essential immune mediator in various diseases, including psoriasis. C3 deficiency promoted imiquimod-induced skin cell apoptosis and supported greater proportions of IFN-γ T cells in the inflamed tissues.
Z05188
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Product Introduction
Species Human
Protein Construction
Complement C3 (Ser23-Asn1663)
Accession # P01024		 His
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
Endotoxin Level Less than 1EU per μg by the LAL method.
Expression System HEK293
Theoretical Molecular Weight 188.52 kDa
Apparent Molecular Weight Due to enzyme lysis and glycosylation, the protein migrates to 67-68 kDa, 110-115 kDa and 140-160 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.

Examples
  • Complement C3, His, Human
    • Complement C3, His, Human

    The purity of Complement C3, His, Human is greater than 95% as determined by SEC-HPLC.

  • Complement C3, His, Human
    • Complement C3, His, Human

    Complement C3, His, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.


Background
Target Background Complement component 3 (C3), a pivotal molecule in the complement system, is an essential immune mediator in various diseases, including psoriasis. C3 deficiency promoted imiquimod-induced skin cell apoptosis and supported greater proportions of IFN-γ T cells in the inflamed tissues.
Synonyms Complement component 3;HSE-MSF;C3;CPAMD1;AHUS5;ARMD9;ASP;C3a;C3b;HEL-S-62p

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.