CLEC-1 hFc Chimera, Human
CLEC-1 HFc Chimera, Human

Immobilized CLEC-1 hFc Chimera, Human, hFc Tag at 0.5 μg/ml (100 μl/well) on the plate. Dose response curve for Biotinylated Anti-CLEC-1 Antibody, hFc Tag with the EC50 of 8.0 ng/ml determined by ELISA.

CLEC-1 HFc Chimera, Human

CLEC-1 hFc Chimera, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

CLEC-1 hFc Chimera, Human

C-type lectin-like receptor-1 (CLEC-1) is a member of the Dectin-1 cluster of pattern recognition receptors (PRRs). It is involved in host immunity, has immunoregulatory function, and supports allograft tolerance. CLEC-1 may act as a negative regulator of Dectin-1 induced host inflammatory response via suppressing neutrophils recruitment and production of pro-inflammatory cytokine IL-1β production in response to A. fumigatus keratitis.
Z05171
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Product Introduction
Species Human
Protein Construction
hFc CLEC-1 (Gln74-Asp280)
Accession # Q8NC01
N-term C-term
Purity > 95% as determined by Bis-Tris PAGE
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA. Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 51.2 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 60-70 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.

Examples
  • CLEC-1 HFc Chimera, Human
    • CLEC-1 HFc Chimera, Human

    Immobilized CLEC-1 hFc Chimera, Human, hFc Tag at 0.5 μg/ml (100 μl/well) on the plate. Dose response curve for Biotinylated Anti-CLEC-1 Antibody, hFc Tag with the EC50 of 8.0 ng/ml determined by ELISA.

  • CLEC-1 HFc Chimera, Human
    • CLEC-1 HFc Chimera, Human

    CLEC-1 hFc Chimera, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.


Background
Target Background C-type lectin-like receptor-1 (CLEC-1) is a member of the Dectin-1 cluster of pattern recognition receptors (PRRs). It is involved in host immunity, has immunoregulatory function, and supports allograft tolerance. CLEC-1 may act as a negative regulator of Dectin-1 induced host inflammatory response via suppressing neutrophils recruitment and production of pro-inflammatory cytokine IL-1β production in response to A. fumigatus keratitis.
Synonyms CLEC-1; CLEC1; CLEC1A; MGC34328

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.