CEACAM-3/CD66d hFc Chimera, Human
CEACAM-3/CD66d HFc Chimera, Human

Immobilized Human CEACAM-7, His Tag at 1 μg/ml (100 μI/well) on the plate. Dose response curve for CEACAM-3/CD66d hFc Chimera, Human, hFc Tag with the EC50 of 23.7ng/ml determined by ELISA.

CEACAM-3/CD66d HFc Chimera, Human

The purity of CEACAM-3/CD66d hFc Chimera, Human is greater than 95% as determined by SEC-HPLC.

CEACAM-3/CD66d HFc Chimera, Human

CEACAM-3/CD66d hFc Chimera, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

CEACAM-3/CD66d hFc Chimera, Human

The human granulocyte-specific receptor carcinoembryonic antigen-related cell adhesion molecule (CEACAM)3 is critically involved in the opsonin-independent recognition of several bacterial pathogens. CEACAM3-mediated phagocytosis depends on the integrity of an ITAM-like sequence within the cytoplasmic domain of CEACAM3 and is characterized by rapid stimulation of the GTPase Rac.
Z05163
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Product Introduction
Species Human
Protein Construction
CEACAM-3/CD66d (Lys35-Gly155)
Accession # P40198-1		 hFc
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA. Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 39.85 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 50-60 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.

Examples
  • CEACAM-3/CD66d HFc Chimera, Human
    • CEACAM-3/CD66d HFc Chimera, Human

    Immobilized Human CEACAM-7, His Tag at 1 μg/ml (100 μI/well) on the plate. Dose response curve for CEACAM-3/CD66d hFc Chimera, Human, hFc Tag with the EC50 of 23.7ng/ml determined by ELISA.

  • CEACAM-3/CD66d HFc Chimera, Human
    • CEACAM-3/CD66d HFc Chimera, Human

    The purity of CEACAM-3/CD66d hFc Chimera, Human is greater than 95% as determined by SEC-HPLC.

  • CEACAM-3/CD66d HFc Chimera, Human
    • CEACAM-3/CD66d HFc Chimera, Human

    CEACAM-3/CD66d hFc Chimera, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.


Background
Target Background The human granulocyte-specific receptor carcinoembryonic antigen-related cell adhesion molecule (CEACAM)3 is critically involved in the opsonin-independent recognition of several bacterial pathogens. CEACAM3-mediated phagocytosis depends on the integrity of an ITAM-like sequence within the cytoplasmic domain of CEACAM3 and is characterized by rapid stimulation of the GTPase Rac.
Synonyms CEACAM3; CD66d; CGM1; CEA;

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.