CDH11/Cadherin 11, His, Human
CDH11/Cadherin 11, His, Human

CDH11/Cadherin 11, His, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 90%.

CDH11/Cadherin 11, His, Human

CDH11 belongs to a group of transmembrane proteins that are principally located in adherens junctions. CDH11 mediates homophilic cell-to-cell adhesion, which may promote the development of cirrhosis. CDH11 expression was positively correlated with liver fibrosis in patients with cirrhosis, and could therefore be a prognostic factor in patients with liver fibrosis.
Z05145
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Product Introduction
Species Human
Protein Construction
CDH11/Cadherin 11 (Gly54-Thr617)
Accession # AAA35622.1		 His
N-term C-term
Purity > 90% as determined by Bis-Tris PAGE
Endotoxin Level Less than 1EU per μg by the LAL method.
Expression System HEK293
Theoretical Molecular Weight 66.32 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 67-70 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.

Examples
  • CDH11/Cadherin 11, His, Human
    • CDH11/Cadherin 11, His, Human

    CDH11/Cadherin 11, His, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 90%.


Background
Target Background CDH11 belongs to a group of transmembrane proteins that are principally located in adherens junctions. CDH11 mediates homophilic cell-to-cell adhesion, which may promote the development of cirrhosis. CDH11 expression was positively correlated with liver fibrosis in patients with cirrhosis, and could therefore be a prognostic factor in patients with liver fibrosis.
Synonyms Cadherin-11;OSF-4;Osteoblast cadherin;OB-cadherin;CDH11;CAD11OSF-4; CDHOB;OB

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.