CDCP1, His, Human
CDCP1, His, Human

Loaded Anti-CDCP1 Antibody, hFc-Avi Tag on ProA-Biosensor can bind CDCP1, His, Human, His Tag with an affinity constant of 17.00 nM as determined in BLI assay (Gator® Prime).

CDCP1, His, Human

Immobilized CDCP1, His, Human, His Tag at 2 μg/ml (100 μl/well) on the plate. Dose response curve for Anti-CDCP1 Antibody, hFc Tag with the EC50 of 5.4ng/ml determined by ELISA.

CDCP1, His, Human

The purity of CDCP1, His, Human is greater than 95% as determined by SEC-HPLC.

CDCP1, His, Human

CDCP1, His, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

CDCP1, His, Human

CDCP1, His, Human, His Tag captured on CM5 Chip via anti-His antibody can bind Anti-CDCP1 Antibody, hFc Tag with an affinity constant of 0.18nM as determined in SPR assay (Biacore T200).

CDCP1, His, Human

Tumor metastasis depends on the dynamic regulation of cell adhesion through β1-integrin. The Cub-Domain Containing Protein-1, CDCP1, is a transmembrane glycoprotein which regulates cell adhesion. Overexpression and loss of CDCP1 have been observed in the same cancer types to promote metastatic progression.
Z05142
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Product Introduction
Species Human
Protein Construction
CDCP1 (Phe30-Leu666)
Accession # Q9H5V8-1		 His
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA. Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 72.8 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 100-130 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.

Examples
  • CDCP1, His, Human
    • CDCP1, His, Human

    Loaded Anti-CDCP1 Antibody, hFc-Avi Tag on ProA-Biosensor can bind CDCP1, His, Human, His Tag with an affinity constant of 17.00 nM as determined in BLI assay (Gator® Prime).

  • CDCP1, His, Human
    • CDCP1, His, Human

    Immobilized CDCP1, His, Human, His Tag at 2 μg/ml (100 μl/well) on the plate. Dose response curve for Anti-CDCP1 Antibody, hFc Tag with the EC50 of 5.4ng/ml determined by ELISA.

  • CDCP1, His, Human
    • CDCP1, His, Human

    The purity of CDCP1, His, Human is greater than 95% as determined by SEC-HPLC.

  • CDCP1, His, Human
    • CDCP1, His, Human

    CDCP1, His, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

  • CDCP1, His, Human
    • CDCP1, His, Human

    CDCP1, His, Human, His Tag captured on CM5 Chip via anti-His antibody can bind Anti-CDCP1 Antibody, hFc Tag with an affinity constant of 0.18nM as determined in SPR assay (Biacore T200).


Background
Target Background Tumor metastasis depends on the dynamic regulation of cell adhesion through β1-integrin. The Cub-Domain Containing Protein-1, CDCP1, is a transmembrane glycoprotein which regulates cell adhesion. Overexpression and loss of CDCP1 have been observed in the same cancer types to promote metastatic progression.
Synonyms CDCP1; CD318; SIMA135; TRASK; UNQ2486; PRO5773

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.