Alpha Synuclein, Human
Alpha Synuclein, Human

The purity of Alpha Synuclein, Human is greater than 95% as determined by SEC-HPLC.

Alpha Synuclein, Human

Alpha Synuclein, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

Alpha Synuclein, Human

Alpha-synuclein (α-synuclein) is a small, acidic protein containing 140 amino acids, highly expressed in the brain and primarily localized in the presynaptic terminals. It is found in high concentrations in Lewy Bodies, proteinaceous aggregates that constitute a typical histopathologic hallmark of Parkinson's disease.
Z05012
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Product Introduction
Species Human
Protein Construction
Alpha Synuclein (Met1-Ala140)
Accession # P37840-1
Purity > 95% as determined by Bis­Tris PAGE 
> 95% as determined by HPLC
Endotoxin Level Less than 1EU per μg by the LAL method.
Expression System E.coli
Theoretical Molecular Weight 14.5 kDa
Apparent Molecular Weight The protein has a predicted MW of 14.5 kDa same as Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in 20mM Tris, 150mM NaCl (pH 8.0).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

Examples
  • Alpha Synuclein, Human
    • Alpha Synuclein, Human

    The purity of Alpha Synuclein, Human is greater than 95% as determined by SEC-HPLC.

  • Alpha Synuclein, Human
    • Alpha Synuclein, Human

    Alpha Synuclein, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.


Background
Target Background Alpha-synuclein (α-synuclein) is a small, acidic protein containing 140 amino acids, highly expressed in the brain and primarily localized in the presynaptic terminals. It is found in high concentrations in Lewy Bodies, proteinaceous aggregates that constitute a typical histopathologic hallmark of Parkinson's disease.
Synonyms Alpha-synuclein; NACP; SNCA; PARK1

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.