Adenylosuccinate Lyase, His, Human
Adenylosuccinate Lyase, His, Human

Adenylosuccinate Lyase, His, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

Adenylosuccinate Lyase, His, Human

Adenylosuccinate lyase (ADSL) is an essential enzyme for de novo purine biosynthesis, ADSL functions in de novo purine synthesis (DNPS) and the purine nucleotide cycle. Adenylosuccinate lyase ADSL) deficiency is a defect of purine metabolism affecting purinosome assembly and reducing metabolite fluxes through purine de novo synthesis and purine nucleotide recycling pathways.
Z04995
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Product Introduction
Species Human
Protein Construction
His Adenylosuccinate Lyase (Ala2-Leu484)
Accession # P30566-1
N-term C-term
Purity > 95% as determined by Bis-Tris PAGE
Endotoxin Level Less than 1EU per μg by the LAL method.
Expression System E.coli
Theoretical Molecular Weight 56.28 kDa
Apparent Molecular Weight The protein has a predicted MW of 56.28 kDa same as Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

Examples
  • Adenylosuccinate Lyase, His, Human
    • Adenylosuccinate Lyase, His, Human

    Adenylosuccinate Lyase, His, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.


Background
Target Background Adenylosuccinate lyase (ADSL) is an essential enzyme for de novo purine biosynthesis, ADSL functions in de novo purine synthesis (DNPS) and the purine nucleotide cycle. Adenylosuccinate lyase ADSL) deficiency is a defect of purine metabolism affecting purinosome assembly and reducing metabolite fluxes through purine de novo synthesis and purine nucleotide recycling pathways.
Synonyms ADSL; ASase; Adenylosuccinase; AMPS; ASL

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.