OX40 Ligand/TNFSF4, His, Cynomolgus/Rhesus macaque
OX40 Ligand/TNFSF4, His, Cynomolgus/Rhesus Macaque

Immobilized OX40 Ligand/TNFSF4, His, Cynomolgus/Rhesus macaque, His Tag at 0.5 μg/ml (100 μl/well) on the plate. Dose response curve for Human OX40, hFc Tag with the EC50 of 18.3ng/ml determined by ELISA.

OX40 Ligand/TNFSF4, His, Cynomolgus/Rhesus Macaque

The purity of OX40 Ligand/TNFSF4, His, Cynomolgus/Rhesus macaque is greater than 95% as determined by SEC-HPLC.

OX40 Ligand/TNFSF4, His, Cynomolgus/Rhesus Macaque

OX40 Ligand/TNFSF4, His, Cynomolgus/Rhesus macaque on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

OX40 Ligand/TNFSF4, His, Cynomolgus/Rhesus macaque

Tumor necrosis factor ligand superfamily member 4 (TNFSF4) is also known as glycoprotein Gp34, OX40 ligand (OX40L),which belongs to the tumor necrosis factor family. It is expressed on such cells as DC2s (a subtype of dendritic cells) enabling amplification of Th2 cell differentiation.
Z04953
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Product Introduction
Species Cynomolgus/Rhesus macaque
Protein Construction
His OX40 Ligand/TNFSF4 (Gln81-Leu213)
Accession # A0A2K5TTN0 (Cynomolgus) / A0A1D5QQH7 (Rhesus macaque)
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA. Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 17.01 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 25-38 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.

Examples
  • OX40 Ligand/TNFSF4, His, Cynomolgus/Rhesus Macaque
    • OX40 Ligand/TNFSF4, His, Cynomolgus/Rhesus Macaque

    Immobilized OX40 Ligand/TNFSF4, His, Cynomolgus/Rhesus macaque, His Tag at 0.5 μg/ml (100 μl/well) on the plate. Dose response curve for Human OX40, hFc Tag with the EC50 of 18.3ng/ml determined by ELISA.

  • OX40 Ligand/TNFSF4, His, Cynomolgus/Rhesus Macaque
    • OX40 Ligand/TNFSF4, His, Cynomolgus/Rhesus Macaque

    The purity of OX40 Ligand/TNFSF4, His, Cynomolgus/Rhesus macaque is greater than 95% as determined by SEC-HPLC.

  • OX40 Ligand/TNFSF4, His, Cynomolgus/Rhesus Macaque
    • OX40 Ligand/TNFSF4, His, Cynomolgus/Rhesus Macaque

    OX40 Ligand/TNFSF4, His, Cynomolgus/Rhesus macaque on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.


Background
Target Background Tumor necrosis factor ligand superfamily member 4 (TNFSF4) is also known as glycoprotein Gp34, OX40 ligand (OX40L),which belongs to the tumor necrosis factor family. It is expressed on such cells as DC2s (a subtype of dendritic cells) enabling amplification of Th2 cell differentiation.
Synonyms OX40L; OX-40L; OX4OL; CD252; TNFSF4; OX40 Ligand; CD134 ligand; CD134L; TXGP1; Glycoprotein Gp34

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.