IL-18RAP/IL-18 R beta, His, Cynomolgus

IL-18RAP/IL-18 R beta, His, Cynomolgus

IL-18RAP, also known as IL-18Rβ or IL-1R7, is component of IL-18 receptor complex and its interactions with IL-18R1 mediate signal transduction initiated by IL-18 although it does not directly bind IL-18 in vitro.
Z04832
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Product Introduction
Species Cynomolgus
Protein Construction
IL-18RAP/IL-18 R beta (Phe20-Arg356)
Accession # A0A2K5VDC3		 His
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
> 95% as determined by HPLC
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA. Immobilized IL-18RAP/IL-18 R beta, His, Cynomolgus at 0.2μg/ml (100μl/well) on the plate can bind Anti­IL­18RAP Antibody, hFc Tag. Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 39.47 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 60-68 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

Background
Target Background IL-18RAP, also known as IL-18Rβ or IL-1R7, is component of IL-18 receptor complex and its interactions with IL-18R1 mediate signal transduction initiated by IL-18 although it does not directly bind IL-18 in vitro.
Synonyms IL-18 R beta; ACPL; CD218b; CDw218b; IL-18R-beta; IL-18Rbeta; IL-18RAcP; IL-1R-7; IL-1R7; IL-1RAcPL; IL18RB; IL18RAP; IL-18R-beta; IL-18R-β; IL-18Rβ

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.