FSHB, His, Cynomolgus
FSHB, His, Cynomolgus

The purity of FSHB, His, Cynomolgus is greater than 95% as determined by SEC-HPLC.

FSHB, His, Cynomolgus

FSHB, His, Cynomolgus on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

FSHB, His, Cynomolgus

Fertility is dependent on follicle-stimulating hormone (FSH), a product of gonadotrope cells of the anterior pituitary gland. Hypothalamic gonadotropin-releasing hormone (GnRH) and intra-pituitary activins are regarded as the primary drivers of FSH synthesis and secretion. Both stimulate expression of the FSH beta subunit gene (Fshb), although the underlying mechanisms of GnRH action are poorly described relative to those of the activins.
Z04795
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Product Introduction
Species Cynomolgus
Protein Construction
FSHB (Asn19-Glu129)
Accession # XP_005578391.1		 His
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
> 95% as determined by HPLC
Endotoxin Level Less than 1EU per μg by the LAL method.
Expression System HEK293
Theoretical Molecular Weight 13.58 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 23-30 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

Examples
  • FSHB, His, Cynomolgus
    • FSHB, His, Cynomolgus

    The purity of FSHB, His, Cynomolgus is greater than 95% as determined by SEC-HPLC.

  • FSHB, His, Cynomolgus
    • FSHB, His, Cynomolgus

    FSHB, His, Cynomolgus on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.


Background
Target Background Fertility is dependent on follicle-stimulating hormone (FSH), a product of gonadotrope cells of the anterior pituitary gland. Hypothalamic gonadotropin-releasing hormone (GnRH) and intra-pituitary activins are regarded as the primary drivers of FSH synthesis and secretion. Both stimulate expression of the FSH beta subunit gene (Fshb), although the underlying mechanisms of GnRH action are poorly described relative to those of the activins.
Synonyms FSH-beta; FSH-B; FSHB; Follitropin;FSH-β

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.