EPHA2 hFc Chimera, Cynomolgus
EPHA2 HFc Chimera, Cynomolgus

The purity of EPHA2 hFc Chimera, Cynomolgus is greater than 95% as determined by SEC-HPLC.

EPHA2 HFc Chimera, Cynomolgus

EPHA2 hFc Chimera, Cynomolgus on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

EPHA2 hFc Chimera, Cynomolgus

Ephrin type-A receptor 2 (EPHA2) is a receptor tyrosine kinase (RTK), whose over-expression has been observed in a variety of cancers, including breast cancer. EPHA2 expression may be causally related to tumorigenesis; therefore, it is important to understand how EPHA2 gene (EPHA2) expression is regulated.
Z04782
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Product Introduction
Species Cynomolgus
Protein Construction
EPHA2 (Ala24-Ser534)
Accession # Q1KL86		 hFc
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
> 95% as determined by HPLC
Endotoxin Level Less than 1EU per μg by the LAL method.
Expression System HEK293
Theoretical Molecular Weight 83.1 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 90-100 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

Examples
  • EPHA2 HFc Chimera, Cynomolgus
    • EPHA2 HFc Chimera, Cynomolgus

    The purity of EPHA2 hFc Chimera, Cynomolgus is greater than 95% as determined by SEC-HPLC.

  • EPHA2 HFc Chimera, Cynomolgus
    • EPHA2 HFc Chimera, Cynomolgus

    EPHA2 hFc Chimera, Cynomolgus on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.


Background
Target Background Ephrin type-A receptor 2 (EPHA2) is a receptor tyrosine kinase (RTK), whose over-expression has been observed in a variety of cancers, including breast cancer. EPHA2 expression may be causally related to tumorigenesis; therefore, it is important to understand how EPHA2 gene (EPHA2) expression is regulated.
Synonyms Ephrin type-A receptor 2 ; EC:2.7.10.1; EPHA2

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.