BST1, His, Cynomolgus
BST1, His, Cynomolgus

The purity of BST1, His, Cynomolgus is greater than 95% as determined by SEC-HPLC.

BST1, His, Cynomolgus

BST1, His, Cynomolgus on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

BST1, His, Cynomolgus

BST1 overexpression conferred resistance to sphingosine in yeast. BST1 deletion produced sensitivity to exogenous D-erythro-sphingosine and phytosphingosine and intracellular accumulation of sphingosine 1-phosphate upon exposure to exogenous sphingosine. sphingoid base metabolism is similar in all eukaryotes and suggests that yeast genetics may be useful in the isolation and identification of other genes involved in sphingolipid signaling and metabolism.
Z04751
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Product Introduction
Species Cynomolgus
Protein Construction
BST1 (Gly26-Ala289)
Accession # A0A2K5VGB5
His
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
> 95% as determined by HPLC
Endotoxin Level Less than 1EU per μg by the LAL method.
Expression System HEK293
Theoretical Molecular Weight 30.99 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 40-50 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

Examples
  • BST1, His, Cynomolgus
  • BST1, His, Cynomolgus

    The purity of BST1, His, Cynomolgus is greater than 95% as determined by SEC-HPLC.

  • BST1, His, Cynomolgus
  • BST1, His, Cynomolgus

    BST1, His, Cynomolgus on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.


Background
Target Background BST1 overexpression conferred resistance to sphingosine in yeast. BST1 deletion produced sensitivity to exogenous D-erythro-sphingosine and phytosphingosine and intracellular accumulation of sphingosine 1-phosphate upon exposure to exogenous sphingosine. sphingoid base metabolism is similar in all eukaryotes and suggests that yeast genetics may be useful in the isolation and identification of other genes involved in sphingolipid signaling and metabolism.
Synonyms Antigen BP3; BST-1; Bp-3; Bp3; Ly65; Bst1; BST1; CD157

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.