BCAM, His, Cynomolgus
BCAM, His, Cynomolgus

The purity of BCAM, His, Cynomolgus is greater than 95% as determined by SEC-HPLC.

BCAM, His, Cynomolgus

BCAM, His, Cynomolgus on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

BCAM, His, Cynomolgus

Lutheran/basal cell adhesion molecule (Lu/BCAM) is a transmembrane adhesion molecule expressed by erythrocytes and endothelial cells that can interact with the extracellular matrix protein laminin-α5. In sickle cell disease, Lu/BCAM is thought to contribute to adhesion of sickle erythrocytes to the vascular wall, especially during vaso-occlusive crises.
Z04746
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Product Introduction
Species Cynomolgus
Protein Construction
BCAM (Glu32-Gly548)
Accession # A0A7N9CA99		 His
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
> 95% as determined by HPLC
Endotoxin Level Less than 1EU per μg by the LAL method.
Expression System HEK293
Theoretical Molecular Weight 57.42 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 70-80 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

Examples
  • BCAM, His, Cynomolgus
    • BCAM, His, Cynomolgus

    The purity of BCAM, His, Cynomolgus is greater than 95% as determined by SEC-HPLC.

  • BCAM, His, Cynomolgus
    • BCAM, His, Cynomolgus

    BCAM, His, Cynomolgus on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.


Background
Target Background Lutheran/basal cell adhesion molecule (Lu/BCAM) is a transmembrane adhesion molecule expressed by erythrocytes and endothelial cells that can interact with the extracellular matrix protein laminin-α5. In sickle cell disease, Lu/BCAM is thought to contribute to adhesion of sickle erythrocytes to the vascular wall, especially during vaso-occlusive crises.
Synonyms LU; MSK19; Gplu; CD239; Lutheran;

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.