APRIL/TNFSF13 Trimer, His & Avi & Flag, Cynomolgus
APRIL/TNFSF13 Trimer, His & Avi & Flag, Cynomolgus

Immobilized APRIL/TNFSF13 Trimer, His & Avi & Flag, Cynomolgus, His Tag at 1 μg/ml (100 μl/well) on the plate. Dose response curve for Cynomolgus BCMA, hFc Tag with the EC50 of 1.4 ng/ml determined by ELISA.

APRIL/TNFSF13 Trimer, His & Avi & Flag, Cynomolgus

APRIL/TNFSF13 Trimer, His & Avi & Flag, Cynomolgus on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

APRIL/TNFSF13 Trimer, His & Avi & Flag, Cynomolgus

The APRIL (a proliferation-inducing ligand), also known as TNFSF13, TALL2, TRDL1, and CD256, is a member of the TNF ligand superfamily. Both APRIL and its close relative BAFF bind and signal through the TNF superfamily receptors TACI and BCMA, while BAFF additionally functions through BAFFR.
Z04735
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Product Introduction
Species Cynomolgus
Protein Construction
Flag His APRIL/TNFSF13 Trimer (Lys112-Leu250)
Accession # A0A2K5TJA1
N-term C-term
Purity > 95% as determined by Bis-Tris PAGE
Endotoxin Level Less than 1 EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA. Immobilized APRIL/TNFSF13 Trimer, His & Avi & Flag, Cynomolgus at 1μg/ml (100μl/well) on the plate can bind Cynomolgus/Rhesus macaque BCMA, hFc Tag. Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 52.1 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 55-65 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 150 mM NaCl, 200 mM L-arginine (pH 8.0).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

Examples
  • APRIL/TNFSF13 Trimer, His & Avi & Flag, Cynomolgus
    • APRIL/TNFSF13 Trimer, His & Avi & Flag, Cynomolgus

    Immobilized APRIL/TNFSF13 Trimer, His & Avi & Flag, Cynomolgus, His Tag at 1 μg/ml (100 μl/well) on the plate. Dose response curve for Cynomolgus BCMA, hFc Tag with the EC50 of 1.4 ng/ml determined by ELISA.

  • APRIL/TNFSF13 Trimer, His & Avi & Flag, Cynomolgus
    • APRIL/TNFSF13 Trimer, His & Avi & Flag, Cynomolgus

    APRIL/TNFSF13 Trimer, His & Avi & Flag, Cynomolgus on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.


Background
Target Background The APRIL (a proliferation-inducing ligand), also known as TNFSF13, TALL2, TRDL1, and CD256, is a member of the TNF ligand superfamily. Both APRIL and its close relative BAFF bind and signal through the TNF superfamily receptors TACI and BCMA, while BAFF additionally functions through BAFFR.
Synonyms CD256; TALL2; TALL-2; TNFSF13; APRIL; APRILFLJ57090; TRDL1; TRDL-1; ZTNF2; 2310026N09Rik

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.