GDF15, His, Canine
GDF15, His, Canine

Immobilized GDF15, His, Canine at 1 μg/ml(100 μl/Well) on the plate. Dose response curve for Anti-GDF15 Antibody, hFc Tag with the EC50 of 6.7 ng/ml determined by ELISA.

GDF15, His, Canine

GDF15, His, Canine on Bis-Tris PAGE under reduced (R) condition and Non reducing (N) condition. The purity is greater than 95%.

GDF15, His, Canine

Immobilized GDF15, His, Canine, His Tag at 1 μg/ml (100 μl/well) on the plate. Dose response curve for Human GFRAL, hFc Tag with the EC50 of 7.3ng/ml determined by ELISA.

GDF15, His, Canine

Growth Differentiation Factor 15 (GDF15), also known as NSAID activated gene-1 (NAG-1), is associated with a large number of biological processes and diseases, including cancer and obesity. GDF15 is synthesized as pro-GDF15, is dimerized, and is cleaved and secreted into the circulation as a mature dimer GDF15.
Z04700
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Product Introduction
Species Canine
Protein Construction
His GDF15 (Ala197-Val307)
Accession # A0A8C0TNP6
N-term C-term
Purity > 95% as determined by Bis-Tris PAGE
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA. Test result was comparable to standard batch.
Expression System E.coli
Theoretical Molecular Weight 13.12 kDa
Apparent Molecular Weight The protein migrates to 15-20 kDa under reduced (R) condition and 23-26 kDa under Non reducing (N) condition based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in 50mM HAc (pH 2.9).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in 50mM HAc (pH 2.9).
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.

Examples
  • GDF15, His, Canine
    • GDF15, His, Canine

    Immobilized GDF15, His, Canine at 1 μg/ml(100 μl/Well) on the plate. Dose response curve for Anti-GDF15 Antibody, hFc Tag with the EC50 of 6.7 ng/ml determined by ELISA.

  • GDF15, His, Canine
    • GDF15, His, Canine

    GDF15, His, Canine on Bis-Tris PAGE under reduced (R) condition and Non reducing (N) condition. The purity is greater than 95%.

  • GDF15, His, Canine
    • GDF15, His, Canine

    Immobilized GDF15, His, Canine, His Tag at 1 μg/ml (100 μl/well) on the plate. Dose response curve for Human GFRAL, hFc Tag with the EC50 of 7.3ng/ml determined by ELISA.


Background
Target Background Growth Differentiation Factor 15 (GDF15), also known as NSAID activated gene-1 (NAG-1), is associated with a large number of biological processes and diseases, including cancer and obesity. GDF15 is synthesized as pro-GDF15, is dimerized, and is cleaved and secreted into the circulation as a mature dimer GDF15.
Synonyms GDF-15; MIC-1; NAG-1; PDF; PLAB; PTGFB; GDF15; MIC1; RG-1; Placental TGF-beta; PTGF-beta; PTGFBPTGF-beta; Placental TGF-β; PTGF-β; PTGFBPTGF-β

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.